Familial hyperinsulinaemic hypoglycaemia with epileptic syndrome, cognitive impairment and detected mutation of the ABCC 8 (SUR1) gene: a case report.

Hyperinsulinaemic hypoglycaemia (HH) occurs as a consequence of unregulated insulin secretion from pancreatic beta cells. It is the most common cause of severe and prolonged hypoglycemia in newborns. HH is a major risk factor for brain damage and subsequent neurological disability, which is why the identification, rapid diagnosis, and timely treatment of patients with HH are essential for the prevention of brain damage.

Risk assessment and toxicological research on micro- and nanoplastics after oral exposure via food products.

Plastics are used ubiquitously and have become part of our everyday life. The global production of plastics is rising, which in consequence is leading to increasing amounts of plastics being released into the environment. Recently, the issue of human exposure to micro- and nanoplastic particles and potentially resulting toxicological consequences has been broached, triggered by the discovery of microplastics in foodstuff.

Micro- and nanoplastics - current state of knowledge with the focus on oral uptake and toxicity.

The production and use of plastics has constantly increased over the last 30 years. Over one third of the plastics is used in disposables, which are discarded within three years of their production. Despite efforts towards recycling, a substantial volume of debris has accumulated in the environment and is slowly degraded to micro- and nanoplastics by weathering and aging.

Search for new physics in events with a leptonically decaying Z boson and a large transverse momentum imbalance in proton-proton collisions at = 13 .

A search for new physics in events with a Z boson produced in association with large missing transverse momentum at the LHC is presented. The search is based on the 2016 data sample of proton-proton collisions recorded with the CMS experiment at , corresponding to an integrated luminosity of 35.9 .

Ultrasensitive nanoparticle detection using a portable whispering gallery mode biosensor driven by a periodically poled lithium-niobate frequency doubled distributed feedback laser.

We demonstrate a significant reduction in the limit of label-free detection of individual viral-sized nanoparticles in aqueous solution through the use of a frequency doubled telecom laser constructed from a distributed feedback-periodically poled lithium-niobate (DFB-PPLN) union. By driving a whispering gallery mode biosensor near a wavelength of 650 nm with this device we have detected real-time adsorption steps for particles 36 nm in radius with a signal to noise ratio of 8. The noise equivalent detection limit is ∼20 ag (17 nm radius).