Background: Multi-cancer early detection (MCED) tests may expand cancer screening. Characterizing diagnostic resolution approaches following positive MCED tests is critical. Two trials employed distinct resolution approaches: a molecular signal to predict tissue of origin (TOO) and an imaging-based diagnostic strategy.
View Article and Find Full Text PDFBlood-based tests for multi-cancer early detection (MCED) are being developed to facilitate the detection of various cancer types. The Detecting cancers Earlier Through Elective mutation-based blood Collection and Testing study (DETECT-A) study evaluated an MCED test in 9,911 women, age 65-75, without personal history of cancer. In a analysis, we report on the detection of precancerous neoplasms consequent to MCED testing and follow-up.
View Article and Find Full Text PDFResearchers and environmental managers need big datasets spanning long time periods to accurately assess current and historical water quality conditions in fresh and estuarine waters. Using remote sensing data, we can survey many water bodies simultaneously and evaluate water quality conditions with greater frequency. The combination of existing and historical water quality data with remote sensing imagery into a unified database allows researchers to improve remote sensing algorithms and improves understanding of mechanisms causing blooms.
View Article and Find Full Text PDFA well-documented consequence of global warming is increased psychological distress and climate anxiety, but data gaps limit action. While climate anxiety garners attention, its expression in therapy remains unexplored. Natural language processing (NLP) models can identify climate discussions in therapy, aiding therapists and informing training.
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