[Comparative characterisation of lipopolysaccharides of Rahnella aquatills].

Lipopolysaccharides (LPS) of eight strains of R. aquatilis isolated from different sources have been studied. The studies of neutral monosaccharide composition evidence that all of LPS contain galactose (13.

[Biological activity of native and modified lipopolysaccharides of Pragia fontium].

Modified lipopolysaccharides (LPS) of Pragia fontium were obtained with germanium complexes (IV) of 2-aminobenzoylhydrazon of salicylic aldehyde (2-NH2-H2Bs), 2-hydroxybenzoylhydrazon salicylic aldehyde (2-OH-H2Bs) and nicotinoylhydrazon of salicylic aldehyde (H2Ns). The modification of LPS was confirmed by IR spectroscopy. Comparative investigations of pyrogenic activity of native and modified LPS showed, that only P.

[Effect of succinylation of Klebsiella 45 bacteriophage proteins on specific lytic activity].

Effect of different levels of virions protein acylation on lytic activity, parameters of interaction with sensitive bacterial cells and other biological properties of phages has been studied in experiments on Klebsiella 45 bacteriophage. It was shown that at 5-, 10- and 20% levels of the phage sample acylation the specific lytic activity increased 90, 12 and 8 times, respectively, adsorbtion velocity constant increased 9, 8 and 8 times, respectively, and latent period decreases by 20% in all cases of the development of productive infection caused by succinylated phages. Such chemical modification did not change morphology, antigenic structure of phase virions, did not take essential effect on the spectrum of lytic activity and average yield of infectious phage corpuscles per a sensitive bacterial cell.

[Chemically modified specific immunoglobulins for legionellosis laboratory diagnostics].

On an example of the rabbit antilegionella immunoglobulins (antLegIgRb) and monospecific human serum (antLegSerHum) the influence of a protein with different acylation level on specific and nonspecific activity of the above immunobiopreparations was investigated. It was determined, that 5 % level of chemical modification provides the highest level of augmentation (2.0-2.

[The properties of Pragia fontium bacteria isolated on the territories of Ukraine and the Czech Republic].

The results are presented of the study of the properties (morphological, tinctorial, cultural, biochemical) and primary DNA structure of 28 Pragia fontium strains, 18 of which were isolated in the territory of Ukraine and 10 in the territory of Czechia. The scheme of differentiation of genera Pragia, Budvicia and Leminorella is presented. The GC (guanine + cysteine) content of DNA is 47 +/- 1.