[Melatonin in the combined treatment of cardiovascular diseases].

The aim of the work was to assess effectiveness of melatonin monotherapy (MT) and combined treatment (CT) in aged patients with arterial hypertension (AH) and coronary heart disease (CHD). A group of 170 patients (mean age 64 years) included 61 ones with CHD and 100 with AH. ECG, AP, and echoCG monitoring was performed before and 21 days after treatment along with clinical examination and evaluation of oxidative and antioxidative activities in erythrocytes.

[Melatonin in combined therapy of patients with stable angina and arterial hypertension].

Study of 2 randomized groups of patients with coronary heart disease, stable exertional angina combined with arterial hypertension, receiving traditional treatment and combined therapy with inclusion of melatonin, was performed. All patients (43 persons at the age from 44 to 69 years) before and after treatment underwent daily monitoring of arterial pressure (AP) by system "BR-102 Schiller", Switzerland. As a result of study, in the group of traditional treatment positive dynamics such as significant decrease in average daily values of systolic arterial pressure (SAP) from 159.

[Evaluation of different methods of treatment of patients with stable stenocardia combined with arterial hypertension according to echocardiographic data].

The authors evaluated the influence of three alternative methods of treatment of coronary artery disease (CAD) and stable exertional stenocardia accompanied by arterial hypertension on systolic and diastolic left ventricular (LV) function. The three methods were: conventional therapy with monocinque, chronotherapy with monocinque, and therapy with a combination of monocinque and melatonin. All the 65 patients aged 44 to 69 years underwent echoCG with Vivid 7 ultrasound scanner (USA) before and after the treatment.

[ECG and BP monitoring in patients with stable angina and essential hypertension on therapy with monocinque].

The authors studied ECG and arterial pressure (AP) parameters in 24 patients with stable angina and arterial hypertension aged 57.9 +/- 1.6 years, receiving 14-day complex therapy including administration of monocinque in a dose of 20 mgs 2 times a day.

[Metabolism of sialoglycoproteins of the stomach of rats with experimental diabetes].

Experiments on white non-inbred male rats studied gastric sialoglycoprotein metabolism. It was found that rats with experimental (alloxan) diabetes exhibit enhanced catabolic processes in sialoglycoprotein metabolism characterized by elevated concentrations of free, oligobound sialic acids and sialidase activity in insignificantly elevated concentrations of protein-bound sialic acids.