[The study of HLA-associations of chronic obstructive disease of lungs in conditions of organic-silicon manufacture].

The purpose of study is to examine associations of polymorphic allele genes HLA class II - DRB1, DQA1 and DQB1 and their haplotypic combinations with chronic obstructive disease of lungs in workers of organocilicic manufacture in Chuvash population. The HLA-genotyping was implemented to 50 patients with chronic obstructive disease of lungs and 38 healthy workers of organocilicic manufacture, belonging to Chuvash ethnic population. The genotyping was implemented on three genes HLA: DRB1 (14 alleles), DQA1 (8 alleles) and DQB1 (11 alleles) using multi-primary polymerase chain reaction technique.

[THE CHARACTERISTICS OF CYTOKINE STATUS UNDER DIFFERENT CLINICAL VARIANTS OF GLOMERULONEPHRITIS].

The article presents results of identification of indicators of cytokine status in 58 patients with glomerulonephritis using solid-phase immunoenzyme analysis. It is established that in patients with glomerulonephritis the level of pro-inflammatory and anti-inflammatory cytokines (IL-lβ, IL-2, IL-10 and Ra-IL-1β) circulating in blood is augmented. The differences are established concerning cytokine status of patients depending on clinical type of disease.

[Prenozological changes in homeostasis indices in soldiers serving for a fixed period].

To reveal the prenosological changes occurred in soldiers' organism the dynamics of blood indices (laboratory-and-clinical method) and physiological system parameters (computer express reflexodiagnostics-programme "Diacoms") were studied. 192 soldiers serving for the fixed period were investigated; the mean age is 20.0 +/- 1.

[Topographic and quantitative characteristics of adipose tissue in various aborigines of Siberia (women)].

The main task of the investigation is to prove suitability of the scheme suggested for estimation of the dynamics of fat content in the organism, in order to analyse age changeability of topography and amount of the subcutaneous fat in 254 women of various race-geographic groups in Siberia and populations, belonging to different adaptive groups. Representatives of the central-east-european (Russians), north europeoid (Komi), uralian (Manci) and central-asian (Buryats) race groups have been investigated. Age groups of 18-23 and 24-55 years of age have been compared.