Role of Na,K-ATPase in Bone Remodeling.

The effects of cardiotonic steroids (ouabain and digoxin) on the bone formation were studied using the organotypic tissue culture in combination with confocal microscopy. The expression of α- and α-isoforms of Na,K-ATPase was detected in cells of the bone tissue of 12-day-old chicken embryos. Ouabain in a concentrations 10 M (comparable with its endogenous concentration) can modulate transducer function of Na,K-ATPase and control the growth and proliferation bone tissue cells.

[Cardiometric data as indications to surgical treatment of elderly and senile patients suffering from thyrotoxicosis].

On the basis of studying clinical symptoms of thyrotoxicosis in elderly patients and an analysis of results of investigation of the heart the authors marked out additional indications to surgical treatment of this category of patients. Results of surgical treatment of elderly and senile patients suffering from thyrotoxicosis are also described.

[Specific clinical course of thyrotoxicosis and results of surgical treatment of elderly patients].

Age is one of the most significant risk factors of the development of diseases of the thyroid gland. Hyperthyroidism is much more difficult for diagnosing in elderly patients since its symptoms might be rubbed off and somewhat atypical. Rather often the cardial symptoms in elderly and senile patients are brought to the forefront when there are no other external manifestations of the disease.