Objective: The objective of this study was to develop a single-channel telemetric intramedullary nail that measures anterior-posterior bending strains and determine whether these forces decrease sigmoidally when normalized to the ground reaction force during fracture healing.
Methods: A transverse midshaft femoral osteotomy (1 mm) was stabilized using a customized TriGen intramedullary nail incorporating a strain gauge in the anterior-posterior plane. Fourteen skeletally mature sheep (2-3 years old) were treated in two pilot studies (n = 3/pilot) and a pivotal study (n = 8).
Screening of augmentation materials for use in balloon kyphoplasty (BKP) may be carried out using vertebral bodies (VBs) prepared from fresh cadaveric or animal model spines, but this approach has many drawbacks. Alternatively, a validated synthetic VB augmentation model may be used. In the present work, such a model-a cube (26 mm sides) of low-density polyurethane foam with a centrally located through-thickness cylindrical hole (diameter = 4 mm) completely filled with a bolus of augmentation material-was used to compare two BKP augmentation materials with very different chemistries (a high-viscosity acrylic bone cement (PMMA) and a calcium phosphate bone substitute (CP)) in cyclic compression life tests.
View Article and Find Full Text PDFOne strategy that has been suggested for reducing the operating room time for cemented total joint arthroplasties-and, hence, for reducing the total cost of these procedures-is to accelerate the polymerization of the acrylic bone cement by preheating the powder to 65 degrees C. We quantified the effect of preheating the cement powders on the fracture toughness and fatigue life of 3 cement brands that are widely used in clinical practice. The results suggest judicious selection of cements whose powders are to be preheated for use in cemented arthroplasties.
View Article and Find Full Text PDFBackground: In some countries, commercially available antibiotic powder-loaded acrylic bone cement is routinely used in joint replacement, while, in others, "off-label" formulations are used in selected procedures (where the antibiotic powder is blended manually with the powder of a plain cement in the operating room/theater by either the surgeon or approved personnel). In the latter situation, an arbitrary rather than a rational approach is used for deciding on the amount of the antibiotic that is blended with the cement powder (herein referred to as "the antibiotic powder loading").
Methods And Results: The first objective of this study was to present two methods for estimating the optimum loading of gentamicin sulfate powder that may be blended manually with the powder of a commercially available acrylic bone cement, ABC (Wopt).