Impact of Minimally Manipulated Cell Therapy on Immune Responses in Radiation-Induced Skin Wound Healing.

The current treatment of radiation-induced skin wounds utilizes mainly conventional therapies, including topical steroids, creams, ointments, and hydrogel dressings, which do not take into account the immunologic changes that occur in the skin after radiation exposure. Therefore, it is relevant to consider alternative therapies and their impact on changes in the immune landscape of the skin. The aim of this study was to investigate the effect of allogeneic minimally manipulated keratinocytes and fibroblasts on rat skin repair and the development of immune responses.

Analysis of transcription profiles for the identification of master regulators as the key players in glioblastoma.

Glioblastoma (GBM) is the most common malignant brain tumor with poor overall survival. Current treatment management for GBM has low efficacy, mainly due to high inter-patient heterogeneity. The transcription profiles in GBM define cell properties essential for tumor progression.

Acoustic Waves and Their Application in Modern Fire Detection Using Artificial Vision Systems: A Review.

This paper presents information on the propagation patterns of acoustic waves and their practical application, in particular, in modern fire detection methods that use artificial vision systems and video cameras as intelligent sensors. In practice, the use of artificial intelligence allows the detection of flames in places where the use of typical sensors is impossible or severely limited. Such a system can work together with environmentally friendly acoustic flame extinguishing technology as a standalone platform, or it may cooperate with other modules, which is a new approach in the field of fire protection.

Ultra-small phospholipid nanoparticles in the treatment of combined hyperlipidemia: a randomized placebo-controlled clinical trial.

Background And Purpose: Combined hyperlipidemia is associated with an increased risk of cardiovascular events. This clinical trial investigated phospholipovit (essential phospholipids, Institute of Biomedical Chemistry, Moscow, Russia), an ultra-small phospholipid nanoparticle (micelles), targeted to phospholipids of HDL in lowering non-HDL-cholesterol (non-HDL-C) and triglycerides (TG) levels in patients with combined hyperlipidemia and moderate cardiovascular risk.

Experimental Approach: A randomized, double-blinded, placebo-controlled phase II trial was conducted on 100 patients.

[Surgical treatment of intramedullary spinal cord tumors: a systematic review].

Background: Intramedullary spinal cord tumors are a rare group of central nervous system tumors with special treatment approaches. The main problems are related to optimal time of surgery, invasiveness and recurrence of tumor.

Objective: To review available literature data on the treatment of intramedullary spinal cord tumors, to summarize the main achievements and changes in treatment strategy over the past 5 years.