Superimposed Wavefront Imaging of Diffraction-enhanced X-rays: sparsity-aware CT reconstruction from limited-view projections.

Purpose: In this paper, we describe an algebraic reconstruction algorithm with a total variation regularization (ART + TV) based on the Superimposed Wavefront Imaging of Diffraction-enhanced X-rays (SWIDeX) method to effectively reduce the number of projections required for differential phase-contrast CT reconstruction.

Methods: SWIDeX is a technique that uses a Laue-case Si analyzer with closely spaced scintillator to generate second derivative phase-contrast images with high contrast of a subject. When the projections obtained by this technique are reconstructed, a Laplacian phase-contrast tomographic image with higher sparsity than the original physical distribution of the subject can be obtained.

Pathological Complete Response to a Single Dose of Pembrolizumab-Based Chemoimmunotherapy for Squamous Cell Carcinoma of the Lung: A Case Report.

We herein describe a patient with non-small-cell lung cancer who achieved pCR with a single dose of pembrolizumab-based chemoimmunotherapy followed by surgery. A 61-year-old man was referred to our hospital with wheezing and an abnormal chest shadow. Squamous cell carcinoma of the left lower lobe, cT2aN1M0 stage IIB, was diagnosed and pembrolizumab-based chemoimmunotherapy was initiated at the patient's request.

Intravascular ultrasound-guided reentry wiring with tip-detection technique for chronic total occlusion of lower extremity artery disease.

Background: Endovascular therapy is an effective method for revascularization in lower extremity artery disease, but treating chronic total occlusion (CTO) remains challenging. This is particularly true for patients with severe calcification, poor run-off in below-the-knee arteries, or limited access sites, where even guidewire (GW) passage can be difficult and bidirectional approaches are often not feasible. The tip-detection (TD) method has been reported as a useful technique in coronary artery CTO interventions, allowing real-time visualization of the GW tip direction.

One-year clinical outcomes of endovascular revascularization in patients with acute limb ischemia.

Urgent revascularization should be performed to patients with acute limb ischemia (ALI) unless the ischemia is irreversible. In patients with severe ALI and multiple morbidities, surgical revascularization is not feasible; however, endovascular revascularization (EVR) may be an option. This study aimed to examine 1-year clinical outcomes of EVR in patients with ALI and determine prognostic factors.