Publications by authors named "S I Hodgetts"

Article Synopsis
  • Researchers are investigating new ways to replace or regenerate lost neurons in neurodegenerative diseases, specifically through direct reprogramming of astrocytes into neurons by manipulating a protein called PTBP1.
  • Some studies claim that this reprogramming leads to functional neurons and better disease outcomes in animal models, while others challenge these findings, questioning the effectiveness of PTBP1 suppression for this purpose.
  • The review highlights recent advancements in regenerative treatments like stem cell transplants for conditions such as Parkinson's and Alzheimer's, suggesting that differences in astrocyte types may explain the mixed results in research regarding their conversion to neurons.*
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Purpose: To re-audit compliance with an amended sedation protocol following the latest national guidelines. To confirm the improved safety achieved through EEG guidance for drug administration during procedural sedation.

Materials And Methods: Following the revision of the departmental protocol, 14 standards were set.

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Introduction: Sarcopenia is common in children after liver transplantation (LTx). Resistance training (RT) may be effective in combating sarcopenia.

Objectives: The purpose of the study was to test the feasibility and impact of a 12-week RT program on skeletal muscle mass (SMM), muscle strength, physical performance (PP), and child-parent perspectives about RT.

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Central nervous system (CNS) injuries and neurodegenerative diseases have markedly poor prognoses and can result in permanent dysfunction due to the general inability of CNS neurons to regenerate. Differentiation of transplanted stem cells has emerged as a therapeutic avenue to regenerate tissue architecture in damaged areas. Electrical stimulation is a promising approach for directing the differentiation outcomes and pattern of outgrowth of transplanted stem cells, however traditional inorganic bio-electrodes can induce adverse effects such as inflammation.

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Here, we report the frequency-dependent spectrum of ice Ih in the range of 0.2-2 THz. We confirm the presence of a feature that blue-shifts from around 1.

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