[Treatment of cardiac insufficiency in patients with chronic obstructive lung disease].

Course and systematic long-term noliprel therapy of chronic obstructive lung disease (COLD) complicated by chronic pulmonary heart permitted to arrest or significantly slow down further progress of heart remodeling, impairment of systolic and diastolic function of right and left chamber and to decrease pressure in the pulmonary artery. These changes correlated with an improved clinical picture of the disease, increased tolerance to physical exercise, and reduced frequency of progressive right ventricular insufficiency. The integral indicator of clinical symptoms fell down from 12.

[Clinicofunctional condition and quality of life in patients with chronic obstructive pulmonary disease before and after outpatient treatment with fenspiride].

Aim: To study effects of long-term administration of fenspiride in combination with broncholytic drugs on dynamics of clinical symptoms, external respiration function and quality of life in patients with chronic obstructive pulmonary disease (COPD).

Material And Methods: A comparative randomized trial of fenspiride used for 6 months in combination with broncholytic drugs enrolled 68 COPD patients. A clinical status, external respiration function were examined.

[Hartil effects on structural-functional condition of the heart in patients with chronic cor pulmonale].

Aim: To study effects of long-term administration of ACE inhibitor ramipril (hartil) on renin-angiotensin-aldosteron system (RAAS), dynamics of clinical symptoms of the disease and structural-functional indices of the right and left ventricle (RV, LI) in patients with chronic obstructive pulmonary disease (COPD) with decompensated chronic cor pulmonale (CCP).

Material And Methods: X-ray examination, echocardiography (echo-CG), investigation of external respiration function were made in 45 patients with non-exacerbated COPD with CCP. The study group consisted of 25 COPD patients with CCP.

[The effectiveness of fenspiride in the treatment of patients with chronic obstructive pulmonary disease].

The purpose of the study was to assess the effectiveness and safety of long-term application of fenspiride, an anti-inflammatory drug, in patients with chronic obstructive pulmonary disease (COPD) under outpatient conditions. The drug was studied on 24 COPD patients. Fenspiride application resulted in improvement in bronchoobstructive syndrome and external respiration parameters, as well as a significant increase in exercise tolerance.

[Immunological and pathogenetic aspects of imunofan administration in aged patients with duodenal ulcer].

Aim: To specify immunological and pathogenetic aspects of imunophan use in aged patients with duodenal ulcer (DU).

Material And Methods: Imunophan was given to 24 DU patients (mean age 62.0 +/- 1.