Pharmaceutical Composition for Improving Physical Working Capacity.

For development of a pharmaceutical composition improving physical performance, effects of various drugs and their combinations on forced swimming test performance were studied on laboratory rats. Maximum increase in animal performance was produced by a 3-component composition asparcam+mildronate+metaprote in proportion of 5.0, 10.

Effects of drugs on exercise performance.

The effects of 15 preparations with general tonic, antioxidant, and antihypoxant activities on exercise performance of laboratory rats were studied in the forced swimming test. The best recovery and improvement of exercise performance was recorded after a single intragastric dose of schizandrin and acyzol. These drugs stimulated an increase in the parameters in control animals by 86 and 72% (exercise performance recovery) and by 33 and 51% (exercise performance improvement).