Publications by authors named "S Hurford"
Background: The Augmented versus Routine Approach to Giving Energy Trial (TARGET) was a 4000-patient trial in which augmented enteral calorie dose did not influence outcomes.
Aim: We aimed to quantify practice change following TARGET.
Methods: Three single-day, prospective, multicentre, point-prevalence audits of adult patients receiving enteral nutrition (EN) in participating Australian and New Zealand intensive care units at 10:00 AM were conducted: (i) 2010 (before conducting TARGET); (ii) 2018 (immediately before publishing TARGET results); and (iii) 2020 (2 years after TARGET publication).
Patients with diabetes represent almost 20% of all ICU admissions and might respond differently to high-dose early active mobilization. To assess whether diabetes modified the relationship between the dose of early mobilization on clinical outcomes in the TEAM trial. All TEAM trial patients were included.
View Article and Find Full Text PDFTo quantify current protein prescription and delivery in critically ill adults in Australia and New Zealand and compare it with international guidelines. Prospective, multicentre, observational study. Five intensive care units (ICUs) across Australia and New Zealand.
View Article and Find Full Text PDFTo describe the protocol and statistical analysis plan for the Treatment of Invasively Ventilated Adults with Early Activity and Mobilisation (TEAM III) trial. An international, multicentre, parallel-group, randomised controlled phase 3 trial. Intensive care units (ICUs) in Australia, New Zealand, Germany, Ireland, the United Kingdom and Brazil.
View Article and Find Full Text PDFArticle Synopsis
- The TARGET Protein trial will assess whether increasing dietary protein intake in ICU patients, as recommended by international guidelines, leads to better health outcomes compared to current practices.
- This clinical trial involves eight ICUs in Australia and New Zealand, where each ICU will switch between two different enteral nutrition formulas over a period of 12 months.
- The main goal is to see if higher protein intake reduces the number of days patients spend in the hospital and improves survival rates at 90 days post-admission.