A PDA (personal digital assistant) program containing information on 193 laboratory tests was provided to students during the 8-week core clerkship in internal medicine. Students used the program at their own discretion. The number of times each test was accessed during the clerkship was recorded by the program's database.
View Article and Find Full Text PDFWe provided a laboratory test program for the personal digital assistant (PDA) to a cohort of third year medical students during their internal medicine clerkship. At the end of each rotation, students were interviewed about their experience with the program, and tracking information was downloaded from their PDAs. Students found the program helpful and easy to use, accessed it more often during patient care activities than as a study aid, and considered the program a better way to learn about laboratory tests than formal teaching sessions.
View Article and Find Full Text PDFPurpose: Monitoring of androgen independent prostate cancer (AIPC) therapy involves monitoring prostate specific antigen (PSA) blood serum concentrations; however, the reliability of small changes in PSA values has been questioned. We performed a small pilot study to determine whether PET might be a useful monitor of changes during anti-angiogenic therapy in AIPC.
Procedures: Changes in tumor blood flow ([15O] water), blood volume ([11C]CO), 2-deoxy-2-[18F]fluoro-D-glucose (FDG) uptake and metabolic volume were measured before and during thalidomide treatment and compared with changes in PSA in six patients with AIPC.
Assessing prostate metastases is difficult with conventional radiographic modalities as few patients have soft tissue involvement and most have only bone lesions. Even with FDG PET, problems due to decreased avidity compared to other tumor types can occur. We assessed PET's ability to monitor changes in such tumors during an anti-angiogenic therapy.
View Article and Find Full Text PDFIdentification of immunogenic leukemia-associated antigens as target structures is mandatory for specific immunotherapy of leukemia. Here, we define acute myeloid leukemia (AML) antigens eliciting a humoral immune response in the autologous host. We applied the method of serologic screening of cDNA expression libraries with autologous serum (SEREX).
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