Epithelial cell surface sites involved in the polyvalent adherence of Porphyromonas gingivalis: a convincing role for neuraminic acid and glucuronic acid.

We investigated the target structures of the epithelial cells responsible for the attachment of Porphyromonas gingivalis by immunocytofluorimetry, enzyme-linked immunosorbent assay, and confocal microscopy. Integrins (beta1, beta3, and alphaV) and E-cadherin played no significant role. Carbohydrates (such as alpha-D-methylglucoside, L-fucose, D- and L-mannose, N-acetylglucosamine, and N-acetylgalactosamine) had little inhibitory effect on bacterial binding.

[Prevalence of juvenile periodontitis in Ille-et-Vilaine. Study of an orthodontic population].

The incidence of Juvenile Periodontitis was studied in 1600 patients residing in Ille et Vilaine, France. The diagnosis was established by the use of panoramic radiography on orthodontic patients. Among this population of patients only 3 cases of Juvenile Periodontitis were found.