Publications by authors named "S Holst"
The substantial development of microscopic techniques and histological examination methods during the past five decades allowed for many new insights into the histology and microanatomy of Rhizostomeae. The present review focuses on new findings about histologically important structures: nerves, senses, muscles, gonads, zooxanthellae and nematocysts. Different ontogenetic stages of rhizostome species were included in the literature research, supplemented with the authors' unpublished data and figures.
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- - The study reviewed the life cycles and reproductive strategies of Rhizostomeae, revealing that about 30% of valid species have documented life cycles, primarily showing a metagenetic cycle with both asexual and sexual reproduction phases.
- - Most Rhizostomeae species are dioecious (having distinct male and female individuals), but there are exceptions, and different taxa exhibit varying methods of asexual reproduction, with the mode differing between groups like Dactyliophorae and Kolpophorae.
- - The authors suggest more research is needed, such as documenting additional species' life cycles, field studies to locate polyps, and experimental studies to better understand the population dynamics and factors influencing medusa production.
Max Egon Thiel worked as curator of the aquatic invertebrates collection at the Zoological Museum in Hamburg until 1963. Specialising in marine planktonic megafauna, he compiled a broad review of the research history on the Scyphozoa (Coronatae, Cubomedusae, Semaeostomeae) including the Staurozoa (as Stauromedusae), written in German. After publishing major parts in 1936 and 1938, World War II delayed further chapters until 1959 and 1962.
View Article and Find Full Text PDFDevelopment of a medication review intervention by seconding a hospital pharmacist to primary care.
Explor Res Clin Soc Pharm
December 2024
Background: Medication reviews (MRs) are a well-described initiative that improves health outcomes for polypharmacy patients. However, there is limited knowledge about the performance of medication reviews carried out in general practice especially under the leadership of hospital clinical pharmacists. When developing complex interventions, such as MRs, it is essential to describe the development process to ensure transparency and avoid research waste.
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- Malignant sweat gland tumors, particularly eccrine porocarcinoma (EP), are rare, with about 18% of benign eccrine poroma (EPO) cases progressing to EP, highlighting a need for more understanding of EP biology and mutations involved in this transformation.
- Transcriptome profiling of 23 EP and normal skin samples showed significant gene expression diversity and downregulation in EP, including specific genes that indicated a stepwise transition from normal skin to EPO to EP.
- The study suggests that EP has a complex molecular nature linked to tumor development, with potential involvement of the p53 and EGFR pathways, and calls for further research with larger sample sizes to validate these findings.