Publications by authors named "S Holloway"

Assessment of pressure ulcer (PU) risk is important in clinical practice and the need to document it in the patient's record is paramount. Despite national and international guidelines highlighting the need to document PU risk, nursing documentation remains variable. The first article in this series discussed the evidence base underpinning the development of clinical guidelines for PUs, alongside the creation of bundle approach for PU prevention.

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Copy number variants (CNVs) are DNA gains or losses involving >50 base pairs. Assessing CNV effects on disease risk requires consideration of several factors. First, there are no natural definitions for CNV loci.

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Hard-to-heal (chronic) wounds are a challenge to wound care professionals, a burden to the health service and negatively impact affected individuals' quality of life. They also consume a great deal of healthcare resources globally and are found in all settings, including prisons. Therefore, the evaluation of wound care services is essential in order to develop an awareness of where improvement can be made.

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Article Synopsis
  • The age of newly diagnosed breast tumors provides important insights into their causes and potential outcomes, as it reflects the time from when the tumor starts growing until it is detected.
  • Researchers estimate this age using a novel method based on epigenetic changes rather than traditional age-related markers, revealing that younger tumors tend to be more aggressive with higher growth rates and instability.
  • These findings highlight the potential of this epigenetic approach for better risk assessment and early detection of breast cancer by distinguishing between aggressive young tumors and older, more stable ones.
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Assessment of pressure ulcer (PU) risk remains a challenge in clinical practice. The first part of this article (Martin and Holloway, 2024) discussed the evidence base underpinning the development of clinical guidelines for PUs alongside the creation of the bundle approach regarding PU prevention. This article, part two, presents the results of a clinical audit that explores compliance against a PU prevention bundle (the aSSKINg framework) in an adult community nursing setting in the south-east of England.

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