Donor-Acceptor-Donor Dyads with Electron-Rich π-Extended Azahelicenes to Panchromatic Absorbing Dyes.

Panchromatic dyes have been highly useful in the realm of optical devices. Here, we report that panchromatic dyes with heterohelicenes have been successfully synthesized using a donor-acceptor strategy. Our synthesis resulted in the creation of π-extended aza[5]helicene oligomers with butadiyne linkages, which displayed bathochromically shifted absorption and emission spectra.

A Strategy for Polar Crystals with Dipolar Heterohelicenes.

Polar crystals have attracted interest for the applications to polar materials with piezo- and pyroelectricity, and second harmonic generation. Despite their potential utility for flexible polar materials, a strategy for ordering polar helicenes has remained elusive. Here, we demonstrate the creation of polar crystals with unsymmetrically substituted aza[5]helicenes tuned by substituents.

RF-MaloSite and DL-Malosite: Methods based on random forest and deep learning to identify malonylation sites.

Malonylation, which has recently emerged as an important lysine modification, regulates diverse biological activities and has been implicated in several pervasive disorders, including cardiovascular disease and cancer. However, conventional global proteomics analysis using tandem mass spectrometry can be time-consuming, expensive and technically challenging. Therefore, to complement and extend existing experimental methods for malonylation site identification, we developed two novel computational methods for malonylation site prediction based on random forest and deep learning machine learning algorithms, RF-MaloSite and DL-MaloSite, respectively.

π-Conjugated Compounds for Molecular Materials.

Depth of a conjugated system! The chemistry of π-conjugated compounds is discussed by Guest Editors Satoru Hiroto and Jishan Wu in their Editorial for this special issue.

Synthesis of π-Functional Molecules through Oxidation of Aromatic Amines.

In this review, we focus on the synthesis of π-conjugated functional molecules by the oxidation of aromatic amines, which is one of the most effective methods for the construction of C-C, C-N, and N-N bonds between two π-conjugated molecular units, and consider their characteristics and applications. Polyanilines are the most common products of the oxidation of aromatic amines; however, azobenzenes, phenazines, and 1,1'-binaphthyl-2,2'-diamines may be produced in this manner also, depending on the reaction conditions. Recent advances in the methodology of aniline oxidation have led to the development of high-regioselectivity industrial-scale syntheses of optically or electroactive π-functional dyes containing nitrogen atoms.