Publications by authors named "S Hirachan"
The expression of estrogen, progesterone, and HER2 receptors in breast cancer cells helps guide treatment and predict outcomes. When the status of these receptors is heterogeneous, it makes treatment planning more complex. We present the case of a 72-year-old woman with bilateral breast cancer with heterogenous receptor status and subsequent challenges in management.
View Article and Find Full Text PDFArticle Synopsis
- Breast Cancer (BC) cases are rising, but the exact molecular processes involved are not fully understood; long non-coding RNAs (lncRNAs) are emerging as key players in tumor progression.
- A study identified increased levels of a specific lncRNA, LINC00651, in breast cancer tissues compared to normal tissues, and further experiments confirmed its role in promoting cell proliferation, migration, and invasion.
- These findings suggest that LINC00651 could serve as a new therapeutic target for breast cancer treatments, highlighting the need for further research to improve patient outcomes.
Background: Female breast cancer has become the world's most common malignant tumor, displacing lung malignancy, and the incidence of malignant tumors has increased continuously in recent decades. However, the underlying molecular mechanisms of breast tumorigenesis have not been fully elucidated. By consulting the literature, we discovered that the TIMM8A gene could affect oxidative stress and apoptosis in patients with Mohr-Tranebjærg syndrome.
View Article and Find Full Text PDFis a Biomarker That Predicts a Poor Prognosis of Breast Cancer.
Breast Cancer (Dove Med Press)
March 2024
Background: Breast cancer (BC) is increasingly becoming the primary reason for death in women, which sounded the alarm. Thus, finding a novel management target for BC is imminent.
Materials And Methods: The data on gene expression and clinicopathological characteristics were downloaded from The Cancer Genome Atlas (TCGA).
Background: Thyroid nodules, although mostly benign and symptomless, have a small chance of being cancerous, necessitating accurate diagnosis. This study aims to develop and validate a nomogram for differentiating malignant and non-malignant thyroid nodules in individuals with type 2 diabetes.
Methods: The study included 484 patients with both thyroid nodules and type 2 diabetes who underwent thyroid gland lobectomy at Wenzhou Medical University Hospital.