Publications by authors named "S Hieda"
Article Synopsis
- - Alzheimer's disease (AD) is a common form of dementia characterized by progressive neurodegeneration, and amino acids can impact cognitive functions related to the disease.
- - A study showed that hachimijiogan (HJG), a traditional Japanese herbal medicine, had a positive effect when combined with Acetylcholine esterase inhibitors (AChEIs) in improving cognitive function in women with mild AD.
- - Metabolomic analysis indicated that female patients taking HJG exhibited significant increases in plasma metabolites over 6 months, particularly aspartic acid, compared to those receiving only AChEIs.
Article Synopsis
- - The study investigates how cerebral white matter lesions (WML) and regional cerebral blood flow (rCBF) are related to cognitive decline in early-stage cognitive impairment (ESCI) using path analysis.
- - Eighty-three patients with memory loss were assessed through various tests, including brain imaging and cognition evaluations, revealing significant correlations between WML, rCBF, and cognitive scores (MMSE).
- - Findings indicate complex interrelationships among WML and rCBF that affect cognitive function, highlighting the need for further research to understand these mechanisms better.
Alzheimer's disease (AD) is a progressive neurodegeneration and is the most prevalent form of dementia. Intervention at an early stage is imperative. Although three acetylcholinesterase inhibitors (AChEIs) are currently approved for the treatment of mild AD, they are not sufficiently effective.
View Article and Find Full Text PDFObjective: This study sought to: determine anatomically evaluated predictors of the technical failure of inframalleolar angioplasty (IMA), develop a predictive model for unsuccessful IMA, and investigate the effect of IMA on clinical outcomes in patients with chronic limb threatening ischaemia (CLTI).
Methods: This single centre retrospective observational study enrolled 159 patients with CLTI who underwent IMA for de novo occluded lesions between November 2017 and May 2021. These patients were divided into two groups: the Failed IMA group (n = 62) and the Successful IMA group (n = 97).
Hyperbaric oxygen therapy (HBOT) is regarded as one of the therapeutic options added to standard care to improve lower-limb outcomes in patients with chronic limb-threatening ischemia (CLTI). However, the current guidelines specify that HBOT should not be offered instead of revascularization to prevent limb loss in CLTI patients. The aim of the HOTFOOT study is to examine the impact of HBOT on wound healing in CLTI patients after successful endovascular therapy (EVT).
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