Publications by authors named "S Hessam M Mehr"
Retraction notice to "Cerium oxide nanoparticles acts as a novel therapeutic agent for ulcerative colitis through anti-oxidative mechanism" [Life Sci. 278 (2021) 119500].
Life Sci
December 2024
Background: This investigation investigates the anti-inflammatory and fibrinolytic effects of a cocktail of probiotics derived from traditional dairy products in a murine model of ulcerative colitis (UC).
Materials And Methods: A mix of newly isolated probiotics containing , and was characterized and orally administered to inbred eight-week-old C57BL/6 male mice (n = 6). Clinical symptoms, pathohistological changes, and inflammatory and fibrosis markers were analyzed in the existence and absence of probiotics in colitis mice.
Article Synopsis
- Sphingosine-1-phosphate lyase insufficiency syndrome (SPLIS) is a rare genetic disorder linked to severe health issues like nephrotic syndrome, adrenal insufficiency, and various systemic symptoms, primarily caused by mutations in the SGPL1 gene.
- A study of 76 SPLIS patients found that overall survival is around 50%, with survival influenced by factors such as age at diagnosis, organ involvement, whether the patient received a kidney transplant, and specific SGPL1 genotypes.
- Children diagnosed with SPLIS nephropathy before age one have a significantly worse survival rate compared to those diagnosed after one year, highlighting the importance of early diagnosis and potential interventions.
Neurodegenerative diseases (NDDs) are a class of neurological disorders marked by the progressive loss of neurons that afflict millions of people worldwide. These illnesses affect brain connection, impairing memory, cognition, behavior, sensory perception, and motor function. Alzheimer's, Parkinson's, and Huntington's diseases are examples of common NDDs, which frequently include the buildup of misfolded proteins.
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