Publications by authors named "S Hesaraki"

Article Synopsis
  • Researchers created injectable pastes using bioactive compounds and natural polymers for non-invasive bone surgeries, specifically using quercetin-loaded bioactive glass along with sodium alginate and hyaluronic acid.
  • The study confirmed that these pastes could release quercetin in a sustained manner over 200 hours, with optimal release modeled by the Weibull equation.
  • Testing on human-derived stem cells showed that the pastes enhanced alkaline phosphatase activity and the expression of bone-related proteins, indicating the potential of this combination to promote bone formation (osteogenesis) and warrant further in vivo studies.
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Beta-tricalcium phosphate (β-TCP) scaffolds manufactured through the foam replication method are widely employed in bone tissue regeneration. The mechanical strength of these scaffolds is a significant challenge, partly due to the rheological properties of the original suspension. Various strategies have been explored to enhance the mechanical properties.

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We developed a novel method to fabricate copper nanorods in a poly(ether sulfone) (15 wt %) casting solution by a sonochemical reduction of Cu ions with NaBH. The main twist is the addition of ethanol to remove excess NaBH through Cu(0) catalyzed ethanolysis. This enabled the direct use of the resulting copper-containing casting dispersions for membrane preparation by liquid nonsolvent-induced phase separation and led to full utilization of the copper source, generating zero metal waste.

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Non-cement pastes in the form of injectable materials have gained considerable attention in non-invasive regenerative medicine. Different osteoconductive bioceramics have been used as the solid phase of these bone pastes. Mesoporous bioactive glass can be used as an alternative bioceramic for paste preparation because of its osteogenic qualities.

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Asthma is a pulmonary disease and its pathophysiology includes inflammation, obstruction, edema of the airways, and mucus secretions in the airways. Mesenchymal stem cells (MSCs) are self-renewal that use the therapeutic potential of these cells can be applied as treatments of asthma. In this study, the effect of Mesenchyme stem cells on asthma was investigated.

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