Publications by authors named "S Hepsen"
Objective: Resistance to thyroid hormone beta (RTHβ) is a rare disorder characterized by a fairly heterogeneous clinical presentation due to varying degrees of tissue response to thyroid hormone. The study aimed to evaluate the clinical, laboratory features and genotype-phenotype relationship of Turkish patients with RTHβ.
Methods: Patients who underwent a THRB gene analysis between September 2019 and September 2023 were retrospectively reviewed.
Article Synopsis
- - The study investigates the ECG characteristics of 103 acromegaly patients to assess the risk of cardiovascular complications and life expectancy, highlighting the significance of the Tp-e interval and its ratios as indicators of ventricular arrhythmia risk.
- - Results show that patients with both baseline and current ECGs experienced a decrease in heart rate, QRS duration, and several arrhythmia parameters, which were similarly affected regardless of whether the patients were in active or remission stages of the disease.
- - The conclusion emphasizes that treatment leads to improved ventricular arrhythmia parameters in acromegaly patients, which correlates with a significant reduction in IGF-1 levels, even in those with ongoing active disease.
Purpose: ChatGPT has the potential to offer patient-friendly support. Thyroid carcinoma has become increasingly prevalent in recent years. This study aimed to assess ChatGPT's accuracy and adequacy in answering questions about information, management, and emotional support related to thyroid cancer.
View Article and Find Full Text PDFBackground: The ongoing debate regarding the need for screening Cushing's syndrome (CS) in patients with obesity continues. The objectives of this study were to establish the prevalence of CS in the population with obesity and assess how metabolic health status influences cortisol levels following the 1 mg dexamethasone suppression test (DST).
Methods: This retrospective study included 1008 patients with obesity who underwent screening with the 1 mg DST for CS.
There has been an increase in the diagnosis of thyroid nodules in recent years. In addition to the well-known criteria, features that are likely to increase the risk of malignancy are in the research process. In this study, we aimed to evaluate the malignant potential of nodules that expand the thyroid capsule ultrasonographically.
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