Publications by authors named "S Henttinen"
Nat Commun
September 2021
Article Synopsis
- Prostate cancer shows significant variability among patients, making it essential to identify which individuals will benefit most from systemic therapies.
- Through advanced techniques like single-cell ATAC and RNA sequencing, researchers have discovered specific cell subpopulations that respond differently to enzalutamide treatment, including those that can regenerate even after treatment.
- This study highlights the importance of analyzing changes in chromatin and gene expression at the single-cell level to uncover new molecular indicators of treatment response, which could enhance clinical decision-making in prostate cancer care.
