Publications by authors named "S Hedgire"
The use of conventional contrast agents in computed tomography (CT) and magnetic resonance (MR) imaging is often limited in patients with chronic kidney disease (CKD) due to potential nephrotoxicity. Ferumoxytol, originally developed for iron supplementation, has emerged as a promising alternative MR contrast agent that is safer for patients with CKD. This study aims to present our center's experience with ferumoxytol as a contrast agent in CKD patients.
View Article and Find Full Text PDFBackground: Cardiovascular disease (CVD) is a leading cause of death in ANCA-associated vasculitis (AAV). Screening and primary cardiovascular prevention may improve outcomes.
Methods: We identified patients in the 2002-2019 Mass General Brigham AAV cohort with thoracic CT scans obtained for other clinical purposes.
Current and Emerging Approaches to Imaging Large Vessel Vasculitis.
Circ Cardiovasc Imaging
November 2024
Article Synopsis
- Large vessel vasculitides (LVV) are inflammatory disorders that primarily affect large arteries like the aorta, often linked to conditions such as giant cell arteritis and Takayasu arteritis, with age and gender influencing prevalence.
- Giant cell arteritis commonly occurs in individuals over 50, especially women, while Takayasu arteritis typically affects younger women; both require urgent diagnosis to prevent serious complications like blindness or artery damage.
- Noninvasive imaging techniques, such as ultrasound and MRI, have revolutionized the diagnosis and management of LVV, reducing the need for invasive procedures and aiding in monitoring treatment response and disease progression.
ACR Appropriateness Criteria® Nonvariceal Upper Gastrointestinal Bleeding: 2024 Update.
J Am Coll Radiol
November 2024
This document summarizes the relevant literature for the selection of the initial imaging in five clinical scenarios in patients with suspected or known nonvariceal upper gastrointestinal bleeding (UGIB). These clinical scenarios include suspected nonvariceal UGIB without endoscopy performed; endoscopically confirmed nonvariceal UGIB with clear source but treatment not possible or continued bleeding after endoscopic treatment; endoscopically confirmed nonvariceal UGIB without a confirmed source; suspected nonvariceal UGIB with negative endoscopy; and postsurgical or post-traumatic nonvariceal UGIB when endoscopy is contraindicated. The appropriateness of imaging modalities as they apply to each clinical scenario is rated as usually appropriate, may be appropriate, and usually not appropriate to assist the selection of the most appropriate imaging modality in the corresponding clinical scenarios of nonvariceal UGIB.
View Article and Find Full Text PDFArticle Synopsis
- Type 2 myocardial infarction (MI) is linked to an imbalance between coronary supply and demand, and it has a worse prognosis, highlighting the importance of understanding sex-based differences in coronary artery disease (CAD) within this patient group.
- A study involving patients with type 2 MI found that while both sexes had similar overall CAD prevalence, women showed higher rates of ST-segment depression and lower levels of low-attenuation plaque compared to men.
- Despite these differences, the presence of any CAD, obstructive CAD, and total plaque volume were comparable across genders, indicating that sex does not significantly impact the overall burden of coronary artery disease in type 2 MI patients.