Publications by authors named "S Haywood"

Objective: To compare the rate of diagnosing clinically significant prostate cancer (csPCa) in men with elevated PSA stratified by baseline IsoPSA Index, thus assessing IsoPSA's intermediate-term predictive ability for csPCa.

Material And Methods: Single-center retrospective review of consecutive patients (n=1578) who underwent IsoPSA testing from November 2016-August 2022. Data dichotomized into patients with low(≤6) and high IsoPSA Indices (>6).

View Article and Find Full Text PDF

Objectives: To assess whether the effect of sarcopenia on neoadjuvant chemotherapy (NAC) toxicity is modified by borderline renal function (estimated glomerular filtration rate [eGFR] 40-65 mL/min) and whether sarcopenia and borderline renal function are independently associated with NAC toxicity risk.

Patients And Methods: All patients with muscle-invasive bladder cancer (MIBC) who underwent radical cystectomy (RC) between 2010 and 2022, with available cross-sectional imaging prior to NAC initiation, were included. Skeletal mass was measured from axial computed tomography images obtained at the level of the L3 vertebral body, using Aquarius Intuition software.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effects of prolonged ischaemia during partial nephrectomy (PN) on kidney function, highlighting a lack of research in this area despite its clinical importance.
  • Among 1371 patients, the analysis focused on 759 who had assessments on kidney function pre- and post-surgery, looking at recovery rates related to ischaemia type and duration.
  • Findings revealed that while warm ischaemia showed a significant negative impact on kidney recovery after 30 minutes, cold ischaemia maintained higher recovery rates, suggesting the need to limit warm ischaemia duration for better patient outcomes.
View Article and Find Full Text PDF

Background: Although mental health issues among Indonesian adolescents are of growing concern, a psychometrically valid measure of affect in Indonesia to inform related research and prevention and treatment efforts does not exist.

Methods: The present study's aim was to culturally adapt and validate the widely used Positive and Negative Affect Schedule for Children (PANAS-C) among Indonesian adolescents. The original 30-item PANAS-C in English underwent forward and back translations to Bahasa Indonesia (the national language of Indonesia) followed by cognitive interviews with private and public school students ages 12-15 (n = 18).

View Article and Find Full Text PDF