Publications by authors named "S Hatch"
Background: Behavioural and psychological symptoms in dementia (BPSD) are common, can be distressing for persons living with dementia (PLWD), and challenging for caregivers and clinicians. There are few updated clinical practice guidelines available to assist clinicians with the assessment and management of BPSD, including deprescribing of medications. The Canadian Coalition for Seniors' Mental Health (CCSMH) developed Canadian clinical practice guidelines on the assessment and management of BPSD to address these needs.
View Article and Find Full Text PDFEnergy is a common currency for any living organism, yet estimating energy expenditure in wild animals is challenging. Accelerometers are commonly used to estimate energy expenditure, via a dynamic body acceleration (DBA) or time-energy budget approach. The DBA approach estimates energy expenditure directly from acceleration but may lead to erroneous estimates during inactivity when acceleration is zero but energy expenditure is not.
View Article and Find Full Text PDFOnline peer support programs could address mental wellbeing concerns reported by Black students. The current evaluation explored Black university students' motivations, experiences, and perceived impacts of an online mental wellbeing peer support group (Black Students Talk [BST]) in England and Wales. We conducted two focus groups with Black Students Talk attendees and one with facilitators.
View Article and Find Full Text PDFArticle Synopsis
- Life-history theory suggests that trying to raise babies can make animals less likely to survive, but we don't fully understand why.
- Scientists studied pelagic cormorants over 16 years to see how the energy they used while raising chicks affected their survival chances.
- They found that most years, energy use didn't seem tied to survival, and older birds used less energy, probably because they’ve learned to do things more efficiently.
Background: Alpha-1 antitrypsin deficiency (A1ATD) is a life-threatening condition caused by the inheritance of the serpin family A member 1 "Z" genetic variant driving alpha-1 antitrypsin (AAT) protein misfolding in hepatocytes. There are no approved medicines for this disease.
Methods: We conducted a high-throughput image-based small molecule screen using patient-derived induced pluripotent stem cell-hepatocytes (iPSC-hepatocytes).