Publications by authors named "S Hatanaka"
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide with heterogeneous histopathological phenotypes. Although IgAN with membranoproliferative glomerulonephritis (MPGN)-like features has been reported in children and adults, treatment strategies for this rare IgAN subtype have not been established. Here, we present the case of a 56-year-old man with no history of kidney disease who initially presented with nephrotic syndrome.
View Article and Find Full Text PDFNew insights into the metabolic mechanisms of frailty are needed. This study aimed to identify serum metabolites linked to frailty phenotype and its component through gas chromatography-mass spectrometry metabolomic analysis among community-dwelling older individuals. An exploratory, cross-sectional case-control study.
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- Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder that causes low platelet counts and can be treated with a drug called romiplostim, although data on its safety in Japan is limited.
- A 2-year survey involving 1,622 patients was conducted to assess the real-world effectiveness and safety of romiplostim, finding that 94.08% had chronic ITP and most maintained stable dosages throughout treatment.
- Results showed significant improvements in platelet counts and a favorable risk-benefit balance for romiplostim, with only a small percentage of patients discontinuing treatment due to adverse effects or improvements in their symptoms.
Article Synopsis
- This study explores how phase angle (PhA), derived from bioelectrical impedance analysis, relates to chronic inflammation markers in older adults, highlighting its potential as a reflection of cell membrane health and fluid balance.
- A total of 1664 participants were analyzed, revealing significant associations between abnormal levels of C-reactive protein and interleukin-6 with both whole-body and leg PhAs in men, particularly in those without chronic inflammation-related diseases.
- The findings suggest that while PhA can indicate inflammation in older men, it may require additional context for effective inflammation identification in women.
The spatial coherence and the axial brightness of a cold field emission gun, a Schottky field emission gun and a $\mathrm{LaB}_6$ thermionic gun are precisely measured. By analyzing the Airy pattern from a selected area aperture, various parameters including the spatial coherence length are determined. Using the determined coherence length, the axial brightness of the field emission guns is estimated using the equation which we previously derived based on the discussion of the Wigner function of an electron beam.
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