Publications by authors named "S Hassanein"
Precursor messenger RNA (pre-mRNA) is processed into its functional form during RNA polymerase II (Pol II) transcription. Although functional coupling between transcription and pre-mRNA processing is established, the underlying mechanisms are not fully understood. We show that the key transcription termination factor, RNA exonuclease Xrn2 engages with Pol II forming a stable complex.
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- Infraorbital ethmoidal air cells (IOEAc) are a type of ethmoidal cells located beneath the orbit, showing significant anatomical variation in humans.
- A study involving 1260 CT scans aimed to identify and classify these variations, noting the presence of IOEAc in 173 cases (13.7%).
- The new classification system categorized the air cells into five main types with various subtypes, enhancing understanding for clinical practice and future research.
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- Mitochondria are vital for energy production and play important roles in cellular processes and stress responses, particularly in plants facing environmental challenges like drought.
- This study investigates RNA editing patterns in distinct wheat cultivars under drought conditions to better understand how plants adapt to stress.
- Results indicate significant RNA editing, especially C-to-T conversions, affecting protein structure and regulatory functions, with differences in responses between drought-tolerant and sensitive wheat varieties.
Background: Recent discoveries have illustrated that Lin28A is an oncogene in various cancers, particularly acute myeloid leukemia (AML). The upregulation of Lin28A can actively contribute to tumorigenesis and migration processes in multiple organs. Hence, the inhibition of Lin28A can be achieved by applying phytochemical herbals and targeting Lin28A protein using a computer-aided drug design (CAAD) approach.
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- Arbuscular mycorrhiza (AM) is a beneficial relationship between plant roots and fungi that helps plants absorb nutrients and cope with environmental stresses.
- RNA-seq technology was used to analyze the gene expression in tomato roots at 7 and 30 days after being inoculated with the fungus, identifying 1,019 differentially expressed genes (DEGs), with a strong emphasis on plant defense, growth, and nutrient transport.
- The study offers new insights into the role of AM-responsive genes in tomato roots, enhancing our understanding of the interactions between plants and symbiotic fungi over short and long durations.