Therapeutic burden (TB) in hidradenitis suppurativa (HS) is a key factor that may predict responses to biologic treatments, highlighting its importance in clinical decision-making.
A study of 557 HS patients provided insights into the average TB, which was linked to factors such as older age, longer disease duration, and greater disease severity.
Results indicate that understanding TB can help clinicians better assess when to adjust treatment strategies for HS patients based on their individual severity and treatment history.
The study investigates the timing of initiating biological therapy (secukinumab) for managing hidradenitis suppurativa (HS) to improve patient outcomes.
It involves a retrospective analysis of 67 patients who switched to secukinumab after failing previous treatments, with follow-up lasting 24 weeks to evaluate safety and effectiveness.
Results indicate that 41.79% achieved significant improvement, and a lower therapeutic burden (fewer prior treatments) was linked to better responses, supporting the idea that earlier treatment may be beneficial.