Old and new anti-obesity drugs.

Obesity is a pandemic problem that correlates with a cluster of metabolic factors leading to poor cardiovascular outcomes, morbidity, and an increased risk of overall mortality. It is necessary to approach obesity with a comprehensive treatment plan, which may involve lifestyle modifications (diet, exercise, and behavioral therapy) and pharmacological interventions. This article provides an overview of the mechanisms of action, efficacy, and safety of available long-term anti-obesity drugs and introduces other potential agents under investigation.

Insights from the potential impact of pasteurized in zebrafish models of obesity and diabetes.

Obesity, diabetes, and related metabolic and health conditions are significant concerns in societies worldwide, necessitating the development of effective treatment and prevention strategies. Gut microbiota, particularly (), have emerged as key players in the onset of obesity and diabetes due to their impact on metabolic pathways related to food absorption, low-grade inflammation, and insulin signaling. Using have been identified as a promising approach in obesity and diabetes management.

Enhancing childhood obesity management: implementing an obesity registry for Iranian children and adolescents.

Purpose: The rising prevalence of overweight and obesity among children and adolescents is a global public health issue. This trend has led to increased obesity-related comorbidities and a higher risk of adulthood obesity in this sensitive population. This study aims to establish the first obesity registry for Iranian children and adolescents to enhance the understanding of pediatric obesity and its determinants and consequents.

Comparative effects of different beverages on weight loss in adults: a systematic review and network meta-analysis of randomized trials.

Background: There is a lack of clarity on the comparative effects of different beverages on weight loss in adults.

Objective: This study aimed at quantifying and ranking the effects of different beverages on weight loss.

Methods: We searched PubMed, Scopus, and Web of Science up to January 2023.