Publications by authors named "S Hartono"
Classification of Parkinson's disease by deep learning on midbrain MRI.
Front Aging Neurosci
August 2024
Article Synopsis
- Susceptibility map weighted imaging (SMWI) and quantitative susceptibility mapping (QSM) improve the evaluation of nigrosome-1 (N1) and assist in diagnosing Parkinson's disease through deep learning classification algorithms.
- The study compared four diagnostic methods for Parkinson's disease, including a composite marker, two different deep learning models focused on morphological abnormalities and volume, and traditional neuroradiological evaluations.
- Results showed high classification performance across all methods, with the QSM-NMS marker and neuroradiologist evaluations performing the best, indicating good clinical relevance, though further validation is needed for earlier stages of the disease.
Objectives: To examine the long-term validity of the Active Australia Survey in a cardiac rehabilitation population using accelerometry as the reference measure.
Design: Cohort validation study.
Methods: Cardiac rehabilitation participants with coronary heart disease were recruited to a prospective cohort study.
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is associated with anxiety and depression. Few studies have addressed interventions for symptoms of anxiety and depression in this population. To determine the efficacy of interventions for anxiety and depression in patients with AD.
View Article and Find Full Text PDFBackground: Systemic allergic reactions (sARs) following coronavirus disease 2019 (COVID-19) mRNA vaccines were initially reported at a higher rate than after traditional vaccines.
Objective: We aimed to evaluate the safety of revaccination in these individuals and to interrogate mechanisms underlying these reactions.
Methods: In this randomized, double-blinded, phase 2 trial, participants aged 16 to 69 years who previously reported a convincing sAR to their first dose of COVID-19 mRNA vaccine were randomly assigned to receive a second dose of BNT162b2 (Comirnaty) vaccine and placebo on consecutive days in a blinded, 1:1 crossover fashion at the National Institutes of Health.
Aim: To characterise the corticoreticular pathway (CRP) in a case-control cohort of adolescent idiopathic scoliosis (AIS) patients using high-resolution slice-accelerated readout-segmented echo-planar diffusion tensor imaging (DTI) to enhance the discrimination of small brainstem nuclei in comparison to automated whole-brain volumetry and tractography and their clinical correlates.
Materials And Methods: Thirty-four participants (16 AIS patients, 18 healthy controls) underwent clinical and orthopaedic assessments and brain magnetic resonance imaging (MRI) on a 3 T MRI machine. Automated whole-brain volume-based morphometry, tract-based spatial statistics analysis, and manual CRP tractography by two independent raters were performed.