Glioblastoma oncometry.

A prospective study of 20 patients was conducted to determine changes in the computed tomography appearance of glioblastomas seen at the completion of radiation therapy. An interval CT was obtained after 4000 to 4500 cGy to the whole brain and was compared to a similar baseline study. The tumor volume increased in twelve patients by 13 to 878% (mean 126%) and decreased in seven by 13 to 73% (mean 37%).

Congenital arteriovenous malformation rupturing into a true jejunal diverticulum.

Massive hemorrhage from the gastrointestinal tract of an elderly patient due to a hitherto unreported cause is described. A congenital arteriovenous malformation located in the submucosa of a true jejunal diverticulum ruptured into the lumen. Both selective angiographic demonstration and histologic documentation of the bleeding point are presented.

Oncogenic transformation and hyperthermia.

The potential of hyperthermia for producing oncogenic transformation in vitro was assessed using C3H/10T 1/2 mouse embryo cells. Temperatures in the range of 40 degrees to 45 degrees C caused no transformations, whether or not the heat treatment was associated with significant cell killing. In addition modest hyperthermia appreciably reduced the transformation frequencies associated with X-ray doses.