Intramolecular Redox-driven Synthesis of Mono- and Diradical Iridium(III) Complexes: Insights into Molecular and Electronic Structure, Electrochemistry, and Spin-Communication.

Two π-radical complexes containing bisazo-aromatic-centered radical anion (1•-) were synthesized through in-situ electron transfer from metal-to-ligand using [IrI] and 2-(2-Pyridylazo)azobenzene (1) in inert hydrocarbon solvent. These are characterized as diradical [IrIII(1•-)2]+[2]+ and monoradical [IrIII(1•-)Cl2(PPh3)] 3. In contrast, a rare metal-mediated hydrolytic cleavage of the C(sp2)-N bond occurred in protic solvent resulting in quaternary radical complex [IrIII(1•-)(1')(PPh3)]+(4)+.

Protein-functionalized and intrinsically radiolabeled [Re]ReO nanoparticles: advancing cancer therapy through concurrent radio-photothermal effects.

Purpose: Enhancing therapeutic effectiveness is crucial for translating anticancer nanomedicines from laboratory to clinical settings. In this study, we have developed radioactive rhenium oxide nanoparticles encapsulated in human serum albumin ([Re]ReO-HSA NPs) for concurrent radiotherapy (RT) and photothermal therapy (PTT), aiming to optimize treatment outcomes.

Methods: [Re]ReO-HSA NPs were synthesized by a controlled reduction of ReO in HSA medium and extensively characterized.

Assessment of heat-killed expressing Chikungunya virus E2 protein as a candidate vaccine for dual protection against Chikungunya virus and .

The Chikungunya virus (CHIKV) is a mosquito-borne virus with a long history of recurring epidemics transmitted through mosquitoes. The rapid spread of CHIKV has intensified the need for potent vaccines. Escherichia coli (), a vital part of human gut microbiota, is utilized in recombinant DNA technology for cloning.

Rhodamine B embedded silver nanogranules for selective sensing of l-cysteine.

Sensing of amino acid serves as the frontier research area for early diagnosis and monitoring various diseases. Among various amino acids, the sensing of L-Cysteine is much important for detection of human diseases like neurotoxic effect and coronary heart disease which arises due to excess of L-Cysteine. To address this, we propose a very simple method of L-Cys sensing via fluorescence "TURN ON" mechanism involving silver centred Rhodamine B nanogranules (AgNPs/RhB) stabilized via electrostatic interaction.