Publications by authors named "S Harari"
Background: The COVID-19 pandemic has led to significant concern due to its impact on human health, particularly through pneumonia-induced lung damage. Surfactant proteins A and D (SP-A and SP-D) are implicated in COVID-19 lung damage, but the role of surfactant protein B (SP-B) remains unclear.
Methods: We conducted a single-centre, prospective observational study involving 73 hospitalised COVID-19 pneumonia patients.
Introduction: In order to find early selection criteria to improve the longevity of show jumping horses, a specific protocol was designed.
Methods: Before entering competition, young horses selected from extreme stallions for longevity were measured for many traits, including blood parameters. Blood samples were taken from 952 horses aged 2-4 years old, sired by two groups of stallions: one with unfavorable (U) and the other with favorable (F) extreme estimated breeding values for functional longevity.
Article Synopsis
- Lymphangioleiomyomatosis is a rare lung disease primarily affecting women, and the study investigates the safety and effectiveness of the multikinase inhibitor nintedanib after sirolimus has been deemed insufficient or unsuitable.
- Conducted in Milan, the phase 2 study included 30 women who took nintedanib for 12 months, with the main measurement being the change in lung function (FEV) over that period.
- Results showed that participants experienced stable lung function after one year on nintedanib, but a slight decline occurred in lung function during the following year without treatment, with nausea being the most common side effect.
Introduction: Nintedanib is approved for the treatment of idiopathic pulmonary fibrosis (IPF), other forms of progressive pulmonary fibrosis (PPF), and systemic sclerosis-associated interstitial lung disease (ILD). We present global post-marketing safety data for nintedanib in these fibrosing ILDs.
Methods: Data on adverse events in patients with fibrosing ILDs who were treated with nintedanib were collected via spontaneous reporting and solicited reporting in various studies (excluding clinical trials).
Background And Aim: During the last decade, a small number of studies have used speckle tracking echocardiography (STE) to investigate sarcoidosis effect on left ventricular (LV) mechanics in patients without overt heart disease. The present systematic review and meta-analysis has been primarily designed to summarize the main findings of these studies and to examine the overall influence of sarcoidosis on LV-global longitudinal strain (GLS) and left ventricular ejection fraction (LVEF).
Methods: All echocardiographic studies assessing conventional echoDoppler parameters and myocardial strain indices in patients with extracardiac sarcoidosis (ECS) vs.