Publications by authors named "S Hamdy"

Breast cancer remains a challenging health issue, demanding innovative treatment approaches that maximize efficacy while minimizing damage to healthy cells. Targeted therapy offers a promising strategy tailored to the unique characteristics of breast cancer tumors. Gold nanoparticles have been studied in the context of their therapeutic potential towards cancer treatment showing great success.

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Background: For individuals with multiple sclerosis (MS), treatment interruption can result in relapse/recurrence of the disease activity. Currently, there are no consensus guidelines about whether an abrupt stop with a short washout period or gradual tapering is better for fingolimod (Gilenya) cessation. We investigated the impact of the fingolimod discontinuation strategy on the recurrence of disease activity and the rebound occurrence of symptoms during washout.

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Article Synopsis
  • - The study investigates the prevalence of coexisting autoimmune and autoinflammatory diseases (AIIDs) in Egyptian patients with vitiligo and identifies risk factors associated with these conditions.
  • - Out of 294 participants, about 27% had at least one AIID, with autoimmune thyroid disease being the most common, followed by alopecia areata, psoriasis, and rheumatoid arthritis.
  • - Key predictors for the presence of AIIDs in vitiligo patients include age, female gender, disease duration, affected body surface area, and family history of AIIDs.
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  • The study compared the fracture resistance of teeth after two different root canal retreatment techniques: conventional non-surgical retreatment (Conventional-NSR) and selective non-surgical retreatment (Selective-NSR).
  • A total of 33 mandibular first molars were tested for their ability to withstand fracture after undergoing specific aging procedures, with the Selective-NSR group showing significantly higher fracture resistance than the Conventional-NSR group.
  • Results indicated that the Selective-NSR technique not only had a higher average load before fracture but also resulted in fewer non-repairable fractures compared to the Conventional-NSR method.
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