Publications by authors named "S Hakan Tuna"

Introduction: Acupressure and cold application are nonpharmacologic methods that midwives can use for labor pain. The purpose of this study was to determine the effects of ice massage applied to the SP6 acupressure point during labor on labor pain, labor comfort, labor duration, and anxiety.

Methods: A single-masked, randomized controlled trial was conducted with 100 nulliparous women, including 50 in the intervention group and 50 in the control group.

View Article and Find Full Text PDF
Article Synopsis
  • A study explored the effectiveness of using short-read and long-read genome sequencing to identify genetic causes of neurodevelopmental disorders (NDDs) in individuals who previously did not receive a genetic diagnosis.
  • The research involved 692 individuals, finding causal variants in 36% of affected individuals and uncertain variants in another 23%.
  • Long-read sequencing proved beneficial for resolving complex structural variants and improving the overall understanding of genetic contributions to NDDs.
View Article and Find Full Text PDF

In medical genetics, each genetic variant is evaluated as an independent entity regarding its clinical importance. However, in most complex diseases, variant combinations in specific gene networks, rather than the presence of a particular single variant, predominates. In the case of complex diseases, disease status can be evaluated by considering the success level of a team of specific variants.

View Article and Find Full Text PDF

Objective: Studies aiming at illuminating the complex relationships between cancer, obesity, 25-hydroxy vitamin D (25-OHD) deficiency, and body fat percentage are ongoing. The objective of this study was to investigate the relationships between 25-OHD deficiency, visceral fat tissue, and the Beck Depression Inventory (BDI) in cancer patients.

Methods: This study was conducted from 2013 to 2022.

View Article and Find Full Text PDF

Purpose: To evaluate the retention force of a novel conometric system after thermomechanical aging. In addition, the conometric system's retention force was compared with that of the cemented implant-retained crowns.

Materials And Methods: Two systems to retain implant crowns were tested in this study: a conometric system and a cement-retained system.

View Article and Find Full Text PDF