Background: Hypereosinophilic syndrome (HES) is characterized by blood and tissue hypereosinophilia causing organ damage and/or dysfunction. Mepolizumab, an anti-IL-5 antibody, has recently been approved in this indication. In lymphoid variant (L-)HES, eosinophil expansion is driven by IL-5-producing clonal CD3CD4 T cells.
View Article and Find Full Text PDFHealth Res Policy Syst
January 2025
Background: Over the recent years, the self-care program has been a significant policy in the field of health. The WHO recommended self-care for every country and economic setting for reaching universal health coverage, promoting health, keeping the world safe and serving the vulnerable. Conducting a policy analysis study can be useful in closely examining the self-care program's content, process, context and actors.
View Article and Find Full Text PDFBackground: Acquiring new knowledge necessitates alterations at the synaptic level within the brain. Glutamate, a pivotal neurotransmitter, plays a critical role in these processes, particularly in learning and memory formation. Although previous research has explored glutamate's involvement in cognitive functions, a comprehensive understanding of its real-time dynamics remains elusive during memory tasks.
View Article and Find Full Text PDFObjectives: There is a paucity of longitudinal studies examining the relationship between working hours and the development of psychological distress (PD) among US workers. This study utilized a longitudinal approach to examine this relationship.
Methods: The 2010-2019 Medical Expenditure Panel Survey (MEPS) data was utilized.
Background: In Iran, one of the most important and influential sources for financing the Primary Health Care (PHC )is the government budget. This study was conducted with the aim of evaluating the allocation of the PHC budget and evaluating the equality in the allocation of these resources.
Methods: In this applied descriptive-analytical study, the study population included all of Iran's 31 provinces.