Publications by authors named "S Hacker"
Purpose: This study investigated elite German athletes to (1) assess their serum 25(OH)D levels and the prevalence of insufficiency, (2) identify key factors influencing serum 25(OH)D levels, and (3) analyze the association between serum 25(OH)D levels and handgrip strength.
Methods: In this cross-sectional study, a total of 474 athletes (231 female), aged 13-39 years (mean 19.3 years), from ten Olympic disciplines were included.
Article Synopsis
- The study investigates how increasing glucose levels affect gene expression in two types of human limbal fibroblasts: primary healthy (LFCs) and congenital aniridia (AN-LFCs).
- LFCs and AN-LFCs were cultured in either normal glucose (17.5 mM) or high glucose (70 mM) for 48 or 72 hours, and various mRNA and protein expressions related to growth factors, oxidative stress, and hypoxia were analyzed.
- Results showed that higher glucose significantly altered the expression of key markers like TGF-β1, Nrf2, and NFκB, with differing effects between LFCs and AN-LFCs, indicating a complex response to glucose
Purpose: To evaluate the clinical outcomes in the use of a synthetic medial meniscus implant in patients symptomatic after medial meniscectomy and not responsive to nonoperative treatment.
Methods: This single-arm, multicenter, prospective study enrolled subjects between ages 30 and 75 with postmeniscectomy pain. Changes from baseline to 24 months were measured in the pain subscale of the knee injury and osteoarthritis outcome score (KOOS) and in KOOS overall (average of all 5 subscales) in patients that had received a medial meniscus implant.
Elite athletes are high-performance outliers within their specific sports. Even though science seeks to understand the nature of expertise and elite performance, much knowledge remains compartmentalized within subdisciplines. Despite this multidimensionality being acknowledged, an interdisciplinary approach to understanding elite athletes is still rare.
View Article and Find Full Text PDFDietary supplement use is common in older adult drivers: an analysis from the AAA LongROAD study.
BMC Complement Med Ther
August 2024
Background: Dietary supplement (DS) use is common and increasing among older adults, though much data available on use frequencies are from surveys and performed cross-sectionally. This paper sought to assess the frequency and pattern of dietary supplement use among older adults over time.
Methods: A secondary analysis of data from the AAA LongROAD study, a longitudinal prospective cohort study of older adult drivers, using data from baseline and the first two years of follow up included a total of 2990 drivers aged 65-79 years recruited at five study sites across the US from July 2015 to March 2017.