Impact of daily physical therapy over 2 weeks on spinal mobility including objective electronic measurements and function in patients with axial spondyloarthritis.

Background: Patients with axial spondyloarthritis (axSpA) are often compromised by impaired function and mobility. The standardized 2-week inpatient program 'multimodal rheumatologic complex treatment' (MRCT) was designed for patients with axSpA. The Epionics SPINE (ES) is an objective tool validated to assess mobility.

Clinically relevant differences in spinal mobility related to daytime performance in patients with axial spondyloarthritis.

Objective: Patients with axial spondyloarthritis (axSpA) suffer from clinical symptoms like morning stiffness and back pain. Mobility of patients with axSpA is often impaired. The aim of this study is to compare the performance of patients with axSpA regarding mobility measures including performance-based tests and objective electronic assessments with the Epionics SPINE device (ES) at different times of the day compared with healthy controls (HC).

A large-scale comparison of human-written versus ChatGPT-generated essays.

ChatGPT and similar generative AI models have attracted hundreds of millions of users and have become part of the public discourse. Many believe that such models will disrupt society and lead to significant changes in the education system and information generation. So far, this belief is based on either colloquial evidence or benchmarks from the owners of the models-both lack scientific rigor.

Galba: genome annotation with miniprot and AUGUSTUS.

Background: The Earth Biogenome Project has rapidly increased the number of available eukaryotic genomes, but most released genomes continue to lack annotation of protein-coding genes. In addition, no transcriptome data is available for some genomes.

Results: Various gene annotation tools have been developed but each has its limitations.

Patients' awareness towards physical activity in the treatment of axial spondyloarthritis.

Introduction: The course of axial spondyloarthritis (axSpA) is often characterized by impairments in physical function and mobility. Regular physical activity (PA) is a cornerstone of axSpA management. Recent European League Against Rheumatism (EULAR) recommendations for PA have stressed the importance of their implementation.