Optimizing optical neural network design for enhanced compatibility with analog computation.

This paper breaks away from traditional approaches that merely emulate digital neural networks. Using Mach-Zehnder interferometer (MZI) networks as a case study, we explore the impact of the inherent properties of analog computation on performance and identify the characteristics that optical neural networks (ONNs) components should possess to better adapt to these specific properties. Specifically, we examine the influence of analog computation on bias power and activation functions, as well as the impact of optical pruning on ONN's performance.

Prognostic signature based on mitochondria- and angiogenesis-related genes associated with immune microenvironment of multiple myeloma.

Introduction: Mitochondria and angiogenesis play key roles in multiple myeloma (MM) development, but their interrelated genes affecting MM prognosis are under-studied.

Methods: We analyzed TCGA_MMRF and GSE4581 datasets to identify four genes - CCNB1, CDC25C, HSP90AA1, and PARP1 - that significantly correlate with MM prognosis, with high expression indicating poor outcomes.

Results: A prognostic signature based on these genes stratified patients into high- and low-risk groups, with the latter showing better survival.

ApWD40a, a Member of the WD40-Repeat Protein Family, Is Crucial for Fungal Development, Toxin Synthesis, and Pathogenicity in the Ginseng Alternaria Leaf Blight Fungus .

, the primary pathogen that causes ginseng Alternaria leaf blight disease, can lead to a 20-30% reduction in ginseng yield. WD40 repeat-containing proteins are evolutionarily conserved proteins with diverse functions between different organisms. In this study, we characterized the roles of a WD40 repeat-containing protein in .

Clinical efficacy of antibiotic-loaded bone cement and negative pressure wound therapy in multidrug-resistant organisms diabetic foot ulcers: a retrospective analysis.

Objective: The purpose of this study was to investigate the clinical efficacy of antibiotic-loaded bone cement (ALBC) combined with Negative pressure wound therapy (NPWT) aspiration technique in the treatment of multidrug-resistant diabetic foot ulcers (MDRO-DFUs).

Methods: A retrospective analysis of the clinical data of 80 patients with MDROs-DFU who were used Vacuum sealing drainage (VSD) as NPWT excipient and met the inclusion criteria from January 2019 to January 2024 at our hospital. Patients were divided into an experimental group and a control group, with 40 cases in each.

Cooperation of Lactoplantibacillus plantarum and polyethylene microplastics facilitated the disappearance of tetracycline during anaerobic fermentation of whole plant maize.

In agricultural production systems, the harm of both antibiotics and microplastics (MPs) to human health has been an important and continuously concerned issue. A small bagged silage production system was designed to investigate the effects of Lactoplantibacillus plantarum, polyethylene (PE) -MPs and their mixture on the silage fermentation and chemical composition of Tetracycline (TET) -contaminated whole plant maize. In addition, the bacterial community of silage samples was analyzed by using next generation genome sequencing technology.