Publications by authors named "S H Till"
Background: Alarmin cytokine IL-25 promotes type 2 inflammatory responses in disorders such as asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and known targets include ILC2 and Th2 cells. However, other cellular targets for IL-25 remain poorly defined.
Objective: To investigate induction and expression of IL-25 receptor (IL-17RB) by B cells and evaluate responsiveness of IL-17RB-expressing B cells to IL-25 in vitro.
Article Synopsis
- The study aimed to compare the effectiveness of Basic Life Support (BLS) skills on children and infants during transport in an ambulance, analyzing whether being secured to a stretcher made a difference.
- Data was collected from 24 Emergency Medicine Services providers performing BLS on child and infant manikins under various restraint conditions, revealing no major differences in BLS performance between secured and unsecured manikins for children.
- While compression depth for infants showed a statistical difference, it lacked clinical significance, and overall, both child and infant BLS performances fell short of American Heart Association guidelines.
Background: Anterior cruciate ligament (ACL) reconstruction (ACLR) can be successful in restoring knee stability. However, secondary ACL injury, either through graft failure or contralateral injury, is a known complication and can significantly impact the ability of a patient to return successfully to previous activities.
Purpose: To develop and internally validate an interpretable machine learning model to quantify the risk of graft failure and contralateral ACL injury in a longitudinal cohort treated with ACLR.
Article Synopsis
- This study analyzed the long-term outcomes of surgical repairs for full-thickness distal biceps tears, focusing on patient demographics and injury characteristics over a median follow-up of 14.7 years.* -
- The majority of the 66 patients studied were middle-aged men who experienced these injuries due to traumatic movements, and while they reported pain and weakness, most maintained near-normal range of motion and strength post-surgery.* -
- Despite a 24% complication rate among participants, the results showed that most patients returned to full strength and function, validating the effectiveness of surgical intervention for these injuries.*