Role of the Gene in Development, Secondary Metabolism and Virulence.

is the leading cause of aspergillosis, associated with high mortality rates, particularly in immunocompromised individuals. In search of novel genetic targets against aspergillosis, we studied the WOPR transcription factor OsaA. The deletion of the gene resulted in colony growth reduction.

Effect of Cell-Free Supernatants on the Fungal Development, Transcriptome, and Aflatoxin B1 Production of .

Crop contamination by aflatoxin B1 (AFB1), an produced toxin, is frequently observed in tropical and subtropical regions. This phenomenon is emerging in Europe, most likely as a result of climate change. Alternative methods, such as biocontrol agents (BCAs), are currently being developed to reduce the use of chemicals in the prevention of mycotoxin contamination.

Homeobox transcription factor HbxA influences expression of over one thousand genes in the model fungus Aspergillus nidulans.

In fungi, conserved homeobox-domain proteins are transcriptional regulators governing development. In Aspergillus species, several homeobox-domain transcription factor genes have been identified, among them, hbxA/hbx1. For instance, in the opportunistic human pathogen Aspergillus fumigatus, hbxA is involved in conidial production and germination, as well as virulence and secondary metabolism, including production of fumigaclavines, fumiquinazolines, and chaetominine.

Incidence of Emergency Department Visits for Electric Rental Scooters Using Detailed Ridership Data.

Introduction: Electric scooter (e-scooter) rental usage has increased exponentially around the country, expanding to more than 120 cities by the end of 2018. Early attempts to capture the safety effects of widespread adoption of this technology have been hampered by lack of accurate ridership data. Here we describe a 17-month evolution of ridership characteristics in St.