VNS paired with training enhances recognition memory: mechanistic insights from proteomic analysis of the hippocampal synapse.

Introduction: Recognition memory, an essential component of cognitive health, can suffer from biological limitations of stress, aging, or neurodegenerative disease. Vagus nerve stimulation (VNS) is a neuromodulation therapy with the potential to improve cognitive function. This study investigated the effectiveness of multiple sessions of VNS to enhance recognition memory in healthy rodents and the underlying cognitive benefits of VNS by proteomic analysis of the synaptosome.

Effect of Herbal Medicine (Hwanglyeonhaedok-tang) on Insomnia Patients with Bedtime Procrastination: study protocol for a randomized controlled trial.

Objectives: Insomnia, characterized by difficulty initiating or maintaining sleep, affects a significant portion of the global population. Bedtime procrastination, which is a voluntary delay in going to bed, is a major contributing factor to the prevalence of sleep deprivation in modern societies. Hwanglyeonhaedok-tang (HJD decoction) has shown promise in improving the symptoms of insomnia.

Synergistically Inducing Ultrafast Ion Diffusion and Reversible Charge Transfer in Lithium Metal Batteries Using Bimetallic Molybdenum-Titanium MXenes.

Metal batteries have captured significant attention for high-energy applications, owing to their superior theoretical energy densities. However, their practical viability is impeded by severe dendrite formation and poor cycling stability. To alleviate these issues, a 3D-structured bimetallic-MoTiCT based fiber electrode was fabricated in this study and analyzed experimentally and computationally.

The Effect of Nerve Growth Factor on Cartilage Fibrosis and Hypertrophy during Chondrogenesis Using Induced Pluripotent Stem Cells.

Nerve growth factor (NGF) is a neurotrophic factor usually involved in the survival, differentiation, and growth of sensory neurons and nociceptive function. Yet, it has been suggested to play a role in the pathogenesis of osteoarthritis (OA). Previous studies suggested a possible relationship between NGF and OA; however, the underlying mechanisms remain unknown.