Publications by authors named "S H How"

The benefits of online homework are widely acknowledged for student learning. Numerous studies have provided evidence supporting the notion that the completion of an adequate amount of traditional homework is associated with enhanced academic success. However, there are inconsistent conclusions on the effect of homework completion on academic performance among the students who were exposed to online homework, particularly in China.

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There are currently over forty degenerative diseases that are correlated with abnormal accumulation of peptide/protein aggregates in the human body, such as Alzheimer's disease. Due to their unique physiochemical properties (e.g.

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Adenosine triphosphate (ATP)-binding cassette (ABC) transporter systems are divided into importers and exporters that facilitate the movement of diverse substrate molecules across the lipid bilayer, against the concentration gradient. These transporters comprise two highly conserved nucleotide-binding domains (NBDs) and two transmembrane domains (TMDs). Unlike ABC exporters, prokaryotic ABC importers require an additional substrate-binding protein (SBP) as a recognition site for specific substrate translocation.

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Article Synopsis
  • Cyanate, a harmful byproduct from cyanide oxidation, can be safely turned into ammonia and carbon dioxide using an enzyme called cyanase, which was improved for stability and reusability by trapping it in biomimetic silica.
  • The entrapped cyanase exhibited double the enzyme activity and maintained better performance at elevated temperatures and after a month at room temperature compared to the free enzyme.
  • By co-entrapping another enzyme, carbonic anhydrase, the process for detoxifying cyanate was made more efficient, requiring less bicarbonate and maintaining significant effectiveness even after five reuse cycles.
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  • This study examined the effectiveness and safety of lower doses of osimertinib (20 mg and 40 mg daily) for patients with advanced NSCLC who had previously failed other treatments, compared to the standard 80 mg daily dose.
  • Researchers analyzed data from 22 patients who had the EGFR T790M mutation and found that lower doses resulted in a notable overall response rate of 77.3%, with median progression-free survival of 10 months and overall survival of 13 months.
  • The findings suggest that even patients with poor performance status (ECOG 3 or 4) experienced decent survival outcomes, emphasizing that lower doses of osimertinib could be a viable treatment
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