Publications by authors named "S H Gaffney"

Background: Many patients require inter-hospital transfer (IHT) to tertiary Emergency Departments (EDs) to access specialty services. The purpose of this study is to determine operational outcomes for patients undergoing IHT to a tertiary academic ED, with an emphasis on timing and specialty consult utilization.

Methods: This study was a retrospective observational cohort study at a tertiary academic hospital from 10/1/21-9/30/22.

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Objectives: To evaluate potential airborne asbestos exposures during brake maintenance and repair activities on a P&H overhead crane, and during subsequent handling of the mechanic's clothing.

Methods: Personal ( = 27) and area ( = 61) airborne fiber concentrations were measured during brake tests, removal, hand sanding, compressed air use, removal and reattachment of chrysotile-containing brake linings, and reinstallation of the brake linings. The mechanic's clothing was used to measure potential exposure during clothes handling.

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Background: Primary splenic abscess is rare and typically presents in patients who are immunocompromised. We present a case of a 47-year-old apparently immunocompetent female patient who was diagnosed with primary splenic abscess from a Salmonella Typhimurium infection following emergency laparotomy.

Case Presentation: A 47-year-old female patient presented with subjective fever and severe epigastric and left flank pain.

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Background: Doravirine is a non-nucleoside reverse transcriptase inhibitor recommended for the treatment of virologically suppressed and treatment naïve people living with HIV. The DRIVE-REAL study aimed to describe the characteristics, treatment patterns, and virological outcomes of doravirine users in a real-world cohort in the UK.

Methods: A retrospective, observational, multi-centre chart review was conducted for 300 adults living with HIV initiating doravirine-containing antiretroviral therapy.

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Article Synopsis
  • Fabry disease is a rare genetic disorder caused by GLA gene mutations leading to various health issues, including cardiovascular problems and kidney failure, making long-term clinical monitoring challenging.
  • The study aimed to explore the connection between estimated glomerular filtration rate (eGFR) and left ventricular mass index (LVMI) with long-term clinical outcomes in individuals with Fabry disease.
  • A review of eight studies revealed that both eGFR and LVMI are significant predictors of important clinical events in Fabry disease, showing consistent results across different patient treatments.
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