Publications by authors named "S H Ewe"
Transcatheter aortic valve implantation (TAVI) has been established as an effective treatment modality in patients with severe aortic stenosis (AS) and the uptake of TAVI is rapidly growing in the Asia-Pacific region. However, there exist a heterogeneity in the management of aortic stenosis and the use of TAVI among countries in the region. Reasons for these differences include anatomic variations, disparity in healthcare resources and infrastructure, and the lack of consensus on the optimal management of AS in the Asia-Pacific region.
View Article and Find Full Text PDFArticle Synopsis
- Transcatheter valve-in-valve (VIV) and valve-in-ring (VIR) therapies for failing mitral bioprosthetic valves are being researched to understand their effectiveness and safety over time.
- A meta-analysis reviewed 34 studies involving 7,047 patients to assess short and long-term outcomes, focusing on complications like mortality, stroke, and procedural success rates.
- Findings indicated high success rates of 94.8% for VIV and 80.5% for VIR, with varying short-term mortality and stroke risks across VIV, VIR, and traditional redo surgical mitral valve replacements (SMVR).
Article Synopsis
- Glycated haemoglobin (HbA1c), a key marker for diabetes, was investigated in older adults without cardiovascular disease to see its role in predicting myocardial ageing.
- A study with 247 participants showed significant correlations between HbA1c levels and various left atrial strain measures, indicating changes in heart function.
- The findings suggest that HbA1c could be a useful biomarker for assessing heart health risks related to ageing, regardless of whether an individual has diabetes.
Article Synopsis
- * Conducted on 122 patients with moderate to severe aortic stenosis, the research identified specific circulating proteins that correlate with higher risks of heart failure, severe symptoms, and mortality.
- * Key proteins linked to inflammation and immune responses were significantly associated with worse outcomes, particularly in patients showing reduced heart strain, suggesting new avenues for assessing patient risk beyond standard imaging methods.
Survival loss linked to guideline-based indications for degenerative mitral regurgitation surgery.
David Vancraeynest Anne-Catherine Pouleur Christophe de Meester Agnès Pasquet Bernhard Gerber See Hooi Ewe
Eur Heart J Cardiovasc Imaging
November 2024
Article Synopsis
- The study evaluated the long-term survival outcomes of 2833 patients with severe degenerative mitral regurgitation (DMR) who underwent surgical correction, guided by various surgical indications.
- Results indicated that patients classified under Class-I triggers experienced significantly lower postoperative survival rates compared to those under Class-IIa triggers or no triggers, with a median follow-up of 8.5 years showing a stark difference in survival percentages.
- Overall, operating on patients with Class-I criteria resulted in a considerable loss of postoperative survival time, suggesting that immediate surgery based on these guidelines may not be the best approach for improving long-term outcomes in DMR patients.