Publications by authors named "S H E N Chang-Qing"
Article Synopsis
- - The article discusses heat stress (HS) in mammals, which disrupts their thermal balance and negatively impacts the development of oocytes and embryos, resulting in economic losses in the livestock industry.
- - It outlines the mechanisms by which HS affects embryonic development, including the generation of reactive oxygen species, endocrine disruption, and molecular changes.
- - The article also explores strategies to mitigate HS effects, such as using antioxidants, enhancing mitochondrial function, gene editing, and improving the animals' rearing environment.
Increased plasma creatine kinase-myoglobin (CK-MB) occurs in patients with acute myocardial infarction (AMI), but its underlying relationship with cytosolic phospholipase A2 (cPLA2) is poorly understood. In the present study we sought to determine cPLA2 activation and its relationship with plasma and myocardial CK-MB level and membrane phospholipids (PLs) in an animal model of AMI. AMI was induced in 60 male Sprague-Dawley rats by ligating the left anterior descending of coronary artery.
View Article and Find Full Text PDFBackground And Aims: Group IIa secretory phospholipase A2 (sPLA2 IIa) induces atherosclerosis by altering systemic lipoprotein mechanism. The aim of this study was to investigate the expression and localization of sPLA2 IIa in atherosclerosis of rat aorta, myocardium and visceral adipose tissue (VAT) and to explore the effect of simvastatin on sPLA2 IIa expression.
Methods: Thirty male Wistar rats were randomly divided into three groups: control group, test group, and simvastatin group.