Two Multicenter, Randomized, Double-Blind, Parallel Group Comparison Studies of a Novel Enhanced Lotion Formulation of Halobetasol Propionate, 0.05% Versus Its Vehicle in Adult Subjects With Plaque Psoriasis.

Unlabelled:

Evaluation of adrenal suppression of a lipid enhanced, topical emollient cream formulation of hydrocortisone butyrate 0.1% in treating children with atopic dermatitis.

Corticosteroids are currently the first line of treatment for patients with atopic dermatitis. In the pediatric population however, the potential impact of adrenal suppression is always an important safety concern. Twenty boys and girls, 5-12 years of age, with normal adrenal function and a history of atopic dermatitis were maximally treated three times daily with a lipid-rich, moisturizing formulation of hydrocortisone butyrate 0.

Actinic keratoses and the incidence of occult squamous cell carcinoma: a clinical-histopathologic correlation.

Background: The ability to clinically diagnose actinic keratoses (AKs) lesions has been taken for granted for some time. The importance of the malignant potential of these lesions is well known. However, a recent Phase IV, multicenter study assessing the long-term benefit of aminolevulinic acid-based photodynamic therapy provided a unique opportunity to prospectively examine the clinical histopathologic correlation of AKs.

Comparative efficacy of once-daily flurandrenolide tape versus twice-daily diflorasone diacetate ointment in the treatment of psoriasis.

Background: Flurandrenolide tape has recently been listed as a group I topical corticosteroid. There are no studies that compare this product to group I ointments in the treatment of steroid-responsive dermatoses.

Objective: Our purpose was to determine the relative efficacy of flurandrenolide (4 microg/cm2) tape versus 0.

Safety and efficacy of 0.5% podofilox gel in the treatment of anogenital warts.

Objective: To determine the safety and efficacy of a new gel formulation of podofilox in the treatment of anogenital warts.

Design: Double-blind, randomized, multicenter, vehicle-controlled investigation.

Setting: Private dermatology practices, university clinics (dermatology, gynecology, and infectious diseases), and contract research organizations.