Synergistic effects of colistin-rifampin-based triple antimicrobial combination therapy against Carbapenem-resistant Pseudomonas aeruginosa: a time-kill assay.

Background: Our research aimed to investigate the potential of in vitro triple antimicrobial synergism against carbapenem-resistant Pseudomonas aeruginosa (CRPA) as a strategy to overcome antimicrobial resistance.

Methods: We used 12 CRPA blood isolates stocked in the Asian Bacterial Bank between 2016 and 2018. All isolates were tested by multi-locus sequencing and carbapenemase multiplex PCR.

Redox-active Co(II) and Zn(II) Pincer Complexes as High-Capacity Anode Materials for Lithium-Ion Batteries.

To address the ongoing demand for high-performance energy storage devices, it is crucial to identify new electrode materials. Lithium-ion batteries (LIBs) store energy via the electrochemical redox process, so their electrode materials should have reversible redox properties for rechargeability. On that note, redox-active metal complexes are explored as innovative electrode materials for LIBs.

Influence of Organ-Specific Extranodal Involvement on Survival Outcomes in Stage IV Diffuse Large B-Cell Lymphoma.

Background: The prognostic significance of extranodal sites in stage IV diffuse large B-cell lymphoma (DLBCL) remains uncertain, making it challenging to select appropriate treatment strategies for individual patients. In this study, we aimed to evaluate the influence of different extranodal sites on prognosis in young patients with stage IV DLBCL who achieved complete remission (CR) following initial chemo-immunotherapy and to explore the potential of autologous hematopoietic stem cell transplantation (ASCT) as a consolidation treatment for specific patient subgroups.

Methods: We retrospectively reviewed data from 119 patients with DLBCL aged < 60 years who achieved CR after chemo-immunotherapy between 2008 and 2020.

Solvent-Tuned Plasticity for Various Binder-Free Applications of a New Lead-Free Manganese Halide.

The development of efficient color conversion layers for μ-LED technology faces significant challenges owing to the limitations of materials that require binders. Binders are typically used to ensure uniform film formation in color-conversion layers, but they often cause optical losses, increase layer thickness, and introduce long-term stability issues. To address the limitations of materials requiring binders, cyclopropyltriphenylphosphonium manganese tetrabromide (CPTPMnBr) is synthesized, a novel lead-free metal halide.

Neurotoxic effects of citronellol induced by the conversion of kynurenine to 3-hydroxykynurenine.

Citronellol is widely utilized in consumer products, including cosmetics, fragrances, and household items. However, despite being considered a relatively safe chemical, the health effects and toxicity mechanisms associated with exposure to high concentrations of citronellol, based on product content, remain inadequately understood. Here, we aimed to analyze the neurological effects of citronellol in zebrafish larvae using behavioral and histological analyses and elucidate the mechanisms underlying its neurotoxicity in vivo.